People with obsessive-compulsive disorder (OCD) have high levels of brain inflammation, a discovery researchers say could lead to new treatments.
In OCD, people typically have frequent, upsetting thoughts that they try to control by repeating certain rituals or behaviors, such as washing hands or checking door locks.
Canadian researchers compared 20 OCD patients and a control group of 20 people without the condition. In the OCD patients, inflammation was 32 percent higher in six brain regions that play a role in OCD, according to the study.
"Our research showed a strong relationship between brain inflammation and OCD, particularly in the parts of the brain known to function differently in OCD. This finding represents one of the biggest breakthroughs in understanding the biology of OCD, and may lead to the development of new treatments," senior author Dr. Jeffrey Meyer said.
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