Childhood socioeconomic status and adult brain size: Childhood socioeconomic status influences adult hippocampal size - abstract

Chris Engel 2/4/132:30 PM

Abstract

Objective:

To investigate in older adults without dementia the relationships between socioeconomic status (SES) in childhood and magnetic resonance imaging (MRI)-derived brain volume measures typical of brain aging and Alzheimer's disease (AD)....

Results:

Analysis shows a significant association between childhood SES and hippocampal volume after adjusting for mental ability at age 11 years, adult SES, gender, and education.

Interpretation:

A significant association between childhood SES and hippocampal volumes in late life is consistent with the established neurodevelopmental findings that early life conditions have an effect on structural brain development. This remains detectable more than 50 years later. ANN NEUROL 2012.

http://onlinelibrary.wiley.com/doi/10.1002/ana.22631/abstract

Staff, et al. Annals of Neurology Volume 71, Issue 5, pages 653–660, May 2012.

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